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Learn about PPB and DICER1
Learn about PPB
Learn about DICER1
What can families do?
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Resources
Judicious DICER1 Testing and Surveillance Imaging Facilitates Early Diagnosis and Cure of Pleuropulmonary Blastoma
Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in DICER1 syndrome: a unique variant of the two-hit tumor suppression model
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies
Pleuropulmonary Blastoma: A Report on 350 Central Pathology–Confirmed Pleuropulmonary Blastoma Cases by the International Pleuropulmonary Blastoma Registry
DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry
Go to PubMed
Go to ClinicalTrials.gov
Resources for health professionals
Help with any questions related to PPB and other DICER1-related cancers
Testing and surveillance guidelines to detect PPB and other DICER1-related cancers in their earliest and most curable form
Schemas, roadmaps, and schedules
Further information regarding treatment of Types I, II, III, and Ir PPB
Our publication of 350 cases
Organizations with additional resources
Children’s Minnesota
GeneReviews
International Ovarian and Testicular Stromal Tumor Registry (OTST)
National Cancer Institute
National Organization for Rare Diseases
Pine Tree Apple Classic Fund
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