Clinicians are invited to connect with the Registry regarding participation of individual patients, potential collaborations and other questions.

Please see separate sections of the website regarding individual tumor types and information regarding DICER1.

Pathologists are invited to connect with the Registry regarding free central pathology review (no charge to institution or patient/family).

• Sending slides for central pathology review
• Sending blocks and/or scrolls
• Sending fresh tissue at time of surgery
• Sending frozen tissue

View the specimen transmittal form.

Left over tumor tissue (tumor tissue removed for a clinical reason but not needed for clinical care) is studied for several purposes:

• To confirm the diagnosis:
  This process, called central review, helps ensure that study results truly represent the tumor that is being studied. This central review is performed through review of slides. Please note that only the slides that are sent can be reviewed, thus if there is a component of the tumor not present on the slides that are sent, that would not be reflected by the review report.
• To look for potential targets:
  This is to determine if there are any genetic alterations in the tumor that may now or in the future be targetable with certain medications. Analysis for potential targets may be done with scrolls or blocks but frozen tissue is preferred.
• To determine impact of certain medications or substances on tumor tissue:
  In certain circumstances, fresh tissue (unpreserved) tissue may be available at the time of surgery. This tissue is critical for cutting edge research and may be used in preclinical models to determine sensitivity of some tumors to certain chemotherapy medications. This is one of the reasons that understanding the diagnosis preoperatively is so important; then procedures can be put in place to allow fresh tissue to be sent during or shortly after surgery.