High dose chemotherapy and autologous stem cell reconstitution has been used in several children with recurrent or metastatic PPB. Despite this relatively small number of cases, HDCT + ASCR has been successful in approximately 50% of cases. This is greater success than might be predicted for a sarcoma and suggests that this treatment should be considered. (see Compilation of HDCT + ASCR Cases). Clinicians are encouraged to contact the Registry for the latest data on such treatments. Consultation with physicians who have used HDCT + ASCR can be arranged.