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The International Pleuropulmonary Blastoma Registry
The International Pleuropulmonary Blastoma Registry
Recommendations
Stem Cell Therapy

High dose chemotherapy and autologous stem cell reconstitution has been used in several children with recurrent or metastatic PPB. Despite this relatively small number of cases, HDCT + ASCR has been successful in approximately 50% of cases. This is greater success than might be predicted for a sarcoma and suggests that this treatment should be considered. (see Compilation of HDCT + ASCR Cases). Clinicians are encouraged to contact the Registry for the latest data on such treatments. Consultation with physicians who have used HDCT + ASCR can be arranged.

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Data and recommendations on this site are conscientiously presented but some are unpublished observations and have not undergone peer review. Consultation with the Registry is encouraged to clarify any topics. The International PPB Registry advises caution in the citation of website information.
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