|
|
 |
Special Studies/Tumor Cytogenetics
Fluorescence in situ hybridization (FISH) can identify trisomy 8, a common but non-specific abnormality in PPB. Trisomy 2, and p53 mutations/deletions have also been described. A number of papers have reported cytogenetic results on individual cases of PPB, and virtually all findings, such as Trisomy 8 (seen in 17/23 studied Registry and literature cases – unpublished Registry compilation), have been non-specific. [see Bibliography, focus: cytogenetics]
The Registry encourages investigators to conduct and report special biologic and molecular studies of PPB.
Tissue Bank
Pathologists are asked to consider sending tissue to the PPB Registry Tissue Bank. For details, see Tissue Bank
|
|
