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The International Pleuropulmonary Blastoma Registry
The International Pleuropulmonary Blastoma Registry
PPB Basic Facts
Constitutional/Sydromic and Familial Disease

The Association of PPB with Lung Cysts and Other Dysplastic Conditions and with Familial Childhood Cancer:

The child with PPB: Constitutional Disease: Lung Cysts & More
“Constitutional” disease means the child is predisposed to abnormalities, as evidenced by dysplastic or neoplastic conditions in the child in addition to PPB.

This is probably genetically determined although the genetic defect in PPB children and their families, if any, has not been elucidated.
The Family of the Child with PPB: Familial Disease

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Data and recommendations on this site are conscientiously presented but some are unpublished observations and have not undergone peer review. Consultation with the Registry is encouraged to clarify any topics. The International PPB Registry advises caution in the citation of website information.
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